Sarsaparilla might help decrease pain and swelling. Some chemicals might also help kill cancer cells or slow down their growth. People use sarsaparilla for cancer, rheumatoid arthritis (RA), psoriasis, and many other conditions.

Sarsaparilla contains a wealth of plant chemicals thought to have a beneficial effect on the human body. Chemicals known as saponins might help reduce joint pain and skin itching, and also kill bacteria. Other chemicals may be helpful in reducing inflammation and protecting the liver from damage.